Estrogen Receptor Transrepresses Brain Inflammation
نویسندگان
چکیده
Estrogen receptors (ERs) have long been implicated in the etiology of multiple sclerosis, but no clear molecular mechanisms have linked ERs to the disease's pathology. Now Saijo et al. (2011) provide evidence that ERβ activates a transrepression pathway that suppresses inflammation and inhibits progression of pathology in a mouse model of multiple sclerosis.
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عنوان ژورنال:
- Cell
دوره 145 شماره
صفحات -
تاریخ انتشار 2011